Which of the following acts as cofactors in enzymatic reactions?

Cofactors are non-protein chemical compounds that are necessary for the biological activity of certain enzymes. Micronutrients, which include vitamins and minerals, serve as essential cofactors in numerous enzymatic reactions. For instance, minerals such as magnesium, zinc, and iron can be crucial for the function of various enzymes in metabolic processes.

Macronutrients, while important for energy and structure (including carbohydrates, proteins, and fats), do not typically act as cofactors. Fatty acids are primarily components of lipids and are not involved in enzymatic functions as cofactors. Therefore, micronutrients are correctly identified as the agents that fulfill the role of cofactors in enzymatic reactions, enabling the enzymes to catalyze biochemical reactions effectively.